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4

Leucine
Why Choose Bulk Powders™

LOWEST PRICES
Would you pay up even a fraction of a cost for obscene celebrity endorsements & humungous advertisement budgets running from thousands to millions of euros or dollars? We bet you wouldn't want to. That's why we are here. We are able to offer you unbeatable prices on major sports nutrition products. By buying directly from the world's leading ingredient manufacturers, eliminating ALL middlemen (distributors, retailers and other commission agents), we are able to offer rock bottom prices on all major sports nutrition products. We shop around the world to provide you with the very best in business, something even big brands don't bother to.
OUTSTANDING QUALITY
We offer world's finest quality proteins, flavouring systems, amino acids and standardised herbal extracts to our customers. You won't find us spiking out proteins with cheap amino acids such as Lysine (which is used as pig feed) and creatine monohydrate to spike up the protein levels. Major companies do that to add more profit margins by adding these cheap amino acids (while using inferior quality protein such as WPC30 or WPC70 in just about every protein product they get their hands on while marketing them as "Highly Anabolic Formula". What you see is what you get from us. 100% pure protein with absolutely zero additives added to it. The protein percentage depicted on the label is for real. A certificate of analysis of every products is available on request. 
HUGE RANGE
We offer some of the largest range of products that actually work! All the ingredients what we have on offer have undergone extensive scientific human trials on their safety as well as effectiveness.
ZERO PROPRIETARY BLENDS
We don't want our customers to lurch in dark when it comes to knowing how much of a particular ingredient is actually inside the bottle he/she has just bought. No pixie dust amounts to make a product look like "Damn! It's Loaded with SO MANY ingredients". Everything is clearly put down and included in legitimate quantities as per as scientific studies.
r-BGH & ANTIBIOTICS FREE PROTEINS
We make sure that the milk proteins you're using are derived from cows/buffaloes which are NOT treated with r-BGH/Antibiotics, are grass fed, free range (and not tied up year along chugging down GMO Corn feed). We guarantee that all the milk proteins (including whey protein concentrate, isolate, hydrolysate, micellar casein, milk protein isolate, hydrolysed casein) are sourced from leading dairies in Denmark, Switzerland and Germany. One simply cannot get a better quality milk from anywhere in the world than these countries.
VEGAN AMINO ACIDS
Did you know that most branched chain amino acid (BCAA) supplements are made with synthetic amino acids, derived from human hair or bird feathers? Because eating human hair or duck feathers is disgusting, we make sure that all amino acid products we carry are manufactured from 100% natural, raw ingredients (vegetables) of non-animal origin. Guaranteed 100% Vegan Amino Acids with near 100% purity. Impurities found in other brands of amino acids can be as much as six times higher.
STATE OF ART MANUFACTURING FACILITY
All the products are manufactured and packaged at our state of manufacturing facility located in the state of Sachsen, Germany - typical to very high German standards - true to it's "Made in Germany" heritage before exported all the way to India. Due to our centralised manufacturing location in Europe and even shorter lead times, we're able to formulate, manufacture and ship the product at a very fast rate which leads to unparalleled product freshness before it reaches your doorstep.
ZERO ARTIFICIAL FLAVOURS & SWEETENERS
95% or more sports nutrition products in the market are currently loaded with potential harmful artificial flavours, sweeteners, colours and preservatives. Potential side effects may include diminished sex drive, gastrointestinal problems, seizures, dizziness, and migraines, blurred vision, allergic reactions, blood sugar increases and weight gain. Taking products that are loaded with artificial colours, sweeteners and potentially dangerous chemicals seems like we are taking a step back from our ultimate goal - to feel and look great. That is why we choose to create only the best, using evidence-based nutrients from the world's top suppliers, in researched doses without any unnecessary, unproven ingredients making sure that they are naturally flavoured and sweetened to perfection.
VEGETARIAN/VEGAN CAPSULES
Many of us knowingly or unknowingly consume non-veg shiny shells derived from cows, pigs and other animals. Approximately 70% of the companies use gelatin capsules which are cheap. Gelatin is an animal by-product that is formed from collagen, a protein obtained from connective tissues, as well as certain organs of animals, which majority of our consumers see as a major drawback. So, absolutely no religious sentiments to play with, we make sure that all of our capsule products are guaranteed 100% vegetarian/vegan and made from pine-derived plant cellulose, or fermented tapioca – 100% safe and traceable while preservative-free, GMO & gluten free, 100% biodegradable and wholly sustainable. Additionally, unlike gelatin capsules, vegetarian capsules have no known potential health risks, even when consumed in a long term scenario as they are 100% natural and nontoxic.

Leucine

What is Leucine?

Leucine could be hailed as one of the most potent natural muscle building supplements known to man. Leucine (C6H13NO2) is an Essential Branched Chain Amino Acid (BCAA) known throughout bodybuilding as the ultimate muscle-builder and fat loss primer.

LEUCINE IS THE ROCK STAR OF AMINO ACIDS

Yes, leucine is the rock star of amino acids — it has its own VIP entrance into the muscle (cell) and it has pull with the club DJs. This is probably the easiest analogy to help you understand the world of the muscle cell.

All cells have a membrane to keep the inside stuff inside and the outside stuff outside. (Note: cell membranes are made mostly of fat [phospholipids] and part of the reason that it’s important to eat enough fat).

Along with the other BCAAs (and a couple other amino acids), leucine has is own VIP entrance (actually called LAT1). So leucine can get into the muscle easily.

Once leucine is in the club (cell) it can go up to the DJs (mTOR and Rheb proteins) who are responsible for getting the party (protein synthesis) started. So, mTOR and Rheb are all like, “Hey man, start protein synthesis!” (I’ll go into more details in another upcoming research review.)

So far, leucine is the only amino acid we know that’s able to directly trigger mTOR and Rheb. This makes leucine the rock star (or if you prefer, Paris Hilton, although I think that’s probably offensive to leucine).

Leucine is essential for achieving a positive nitrogen balance and building lean muscle mass.

Leucine activates an anabolic pathway called the mTOR pathway which stimulates muscle protein synthesis. By increasing Leucine consumption the mTOR pathway is signaled and protein synthesis is increased. No single ingredient has the pure, unadulterated anabolic power that Leucine does. Simply stated, Leucine is essential for achieving a positive nitrogen balance and building lean muscle mass.

Leucine is one of the most concentrated amino acids within the skeletal muscle tissue.

Leucine is one of the three branched chain amino acids (the other two being Isoleucine and Valine) and is extremely important to consume dietary sources or supplements to provide the body with this important BCAA. It is naturally found in nuts, brown rice, whole wheat, cottage cheese chicken and fish. Unlike amino acids, which are metabolized in the liver, BCAAs are metabolized in the muscles and are integral for protein synthesis and for preserving lean muscle tissue. Leucine is one of the most concentrated amino acids within the skeletal muscle tissue.

Leucine is so essential for the body that it is referred to as a ‘limiting nutrient’.

Leucine is so essential for the body that it is referred to as a ‘limiting nutrient’. The body absolutely requires Leucine in order to make use of all of the other amino acids. Without adequate amounts of Leucine all other sources of protein can be deemed useless. In short, without Leucine the body doesn’t function properly and will not make use of protein.

Implications for Athletes/Bodybuilders

Lean Muscle Preservation

Leucine helps to preserve lean muscle tissue. It has been found to work with insulin to promote protein synthesis in skeletal muscle. It is also essential for post workout recovery.

In fact, one study found that adding 2.8g of Leucine to a meal, whether it was high in protein or not, helped to increase muscle protein synthesis by approximately 60%! (1) Another study found 4.4g and 8.3g of Leucine increased muscle protein synthesis by 50-70%! From this research, researchers suggest consuming approximately 3-4g of Leucine to effectively maximize muscle protein synthesis.

“One study found that Leucine increased muscle protein synthesis by as much as 50-70%!”

A study conducted on Leucine consumption found it may prevent muscle loss which is a negative fact of life for the aging population. The study group who consumed a Leucine-rich diet did not experience as great of protein degradation as the other group. The Leucine group experienced a more favorable protein breakdown which was more comparable to a younger participant’s pattern.

Leucine also helps to maintain a positive nitrogen balance. Research found that a positive Leucine balance indicates the body is in a state of protein anabolism and that a negative Leucine balance may suggest catabolism. Simply stated, Leucine is essential for achieving a positive nitrogen balance and building lean muscle mass.

Dieting and Blood Sugar Regulation

During dieting Leucine has been found to be especially helpful for its ability to spare protein degradation. When calories are restricted, the body uses Leucine as a source of gluconeogenesis, by supplementing with Leucine glucose blood levels can be stabilized as Leucine easily and readily converts to glucose. In fact, Leucine has been found to convert to glucose at a much faster rate than the other BCAAs.

Leucine can also supply the body with an energy source during stress, which is essential during extreme dieting or after training.

A study conducted on the different diet variations 30 minutes following resistance training found that the group who consumed a carbohydrate/protein+ Leucine supplement experienced a reduction in protein degradation, this group also showed an increase in skeletal muscle protein synthesis which was significantly greater than the study group who consumed just carbohydrates and protein.

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